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When LTO was first introduced in commit 55a7a94 (Enable LTO and -march=native, 2019-05-29), it was enabled by default on all platforms. Now that it is no longer broken in Nix on Darwin, this old default may be restored. The reported upstream issue (NixOS/nixpkgs#19098) has been resolved and the fix is already included in the `nixpkgs-unstable` branch. This also enables LTO again on platforms other than Darwin, where it was unintentionally disabled by default due to a programming error.
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The old comment by @lrworth was spot on, but ended up drowning under further discussion, which led to LTO being enabled only on Darwin by default except in Nix. While my prime motivation was sorting it out for Nix, I ended up spotting the error for all platforms. 🤷